NF-kB Inhibitor, SN50

SN50是一种NF-κB细胞渗透性抑制肽。它由附着于NF-kB p50核定位序列(NLS)的Kaposi成纤维细胞生长因子(K-FGF)信号肽的疏水区组成。SN50抑制NF-kB活性复合物向细胞核的转移。H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-OH